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Abstract #0249

Motion-robust, multi-slice, real-time MR PRFS Thermometry for MR-guided ultrasound thermal therapy in abdominal organs

Kisoo Kim1, Chris Diederich2, and Eugene Ozhinsky1
1Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, United States

MR temperature monitoring during ultrasound thermal therapy of abdominal organs is challenging due to respiratory motion. It is especially important for hyperthermia therapy, which requires accurate temperature measurements to ensure therapeutic heating within a narrow temperature window (37-45 °C). In this study we developed a motion-robust, multi-slice, real-time MR thermometry sequence and reconstruction pipeline for the monitoring of temperature in hyperthermia or thermal ablation therapy in abdominal organs. This technique was implemented in RTHawk and evaluated in simulated acquisitions, phantom experiments with a custom-made motion phantom, and in-vivo healthy volunteer experiment without heating.

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