Abstract #0295

Towards differentiation of white matter pathologies through B-tensor encoding.

Ricardo Rios-Carrillo¹, Ricardo Coronado-Leija², Hiram Luna-Munguía¹, Alonso Ramírez-Manzanares³, and Luis Concha¹

¹Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, Mexico, ²Radiology, New York University School of Medicine, New York, NY, United States, ³Centro de Investigación en Matemáticas, Guanajuato, Mexico

This work explores the ability of B-tensor encoding methods to disentangle axonal degeneration and inflammation through DW-MRI. In particular, we tested Q-space trajectory encoding and diffusion tensor distribution imaging. Both methods clearly differentiated between damaged and intact nerves, and showed moderately different diffusion characteristics between the two experimental conditions.

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