Abstract #0378

Arterial, venous and cerebrospinal fluid flow oscillations in real-time phase contrast MRI: type of breathing matters

Maria Marcella Lagana¹, Noam Alperin², Laura Pelizzari¹, Ning Jin³, Domenico Zaca⁴, Marta Cazzoli¹, Giuseppe Baselli⁵, and Francesca Baglio¹

¹CADiTeR, IRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy, ²University of Miami, Miami, FL, United States, ³MR R&D Collaborations, Siemens Medical Solutions USA, Inc., Cleveland, OH, United States, ⁴Siemens Healthcare, Milan, Italy, ⁵Department of Electronics, Information, and Bioengineering, Politecnico di Milano, Milan, Italy

We used real-time phase contrast MRI for assessing the cardiac and respiratory influence on the neck arterial and venous flows, and on the cervical cerebrospinal fluid (CSF) flow. Changes due to the type of breathing were investigated acquiring six healthy volunteers for 60s during normal and deep breathing. The power spectra were computed from the flow rates. Two main peaks, corresponding to the breathing rate (BR) and the heart rate (HR), were found. Comparing deep breathing to normal breathing, we observed the following trends: decrement of average blood flow rates; reversal of average CSF flow rate; increment of BR power.

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