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Abstract #0379

Phase contrast MRI analysis of neurofluids in patients with Meniere’s disease and jugular venous stenosis.

Nivedita Agarwal1, Olivier Baledent2, Giuseppe Nicolò Frau3, and Sabino Walter Della Sala1
1Radiology, APSS Ospedale Santa Maria del Carmine, Rovereto, Italy, 2University of Amiens, Amiens, France, 3Otorhinolaryngology, APSS Ospedale Santa Maria del Carmine, Rovereto, Italy

Meniere’s disease patients have a high incidence of abnormal neck venous vessels. An inefficient intracranial venous outflow would disturb global neurofluids dynamics and alter intracranial pressure. We used phase contrast MRI to correlate the dynamics of total arterial, total venous and CSF with morphological alterations in internal jugular veins (IJV). Our results show that although >80% of patients have IJV stenosis and isolated CSF and/or blood flow abnormalities, the global neurofluid dynamics remained unhampered. These results underscore the optimal compensation provided by collateral venous pathways and suggests that PC-MRI is an important adjunct clinical tool to to study neurofluids dynamics.

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