Multiparametric renal MRI might be used as a non-invasive biomarker of pediatric chronic kidney disease (CKD). 20 pediatric and young adult healthy controls and 12 patients with CKD underwent quantitative renal MRI consisting of MR elastography (MRE), T1 mapping, T2 mapping, and diffusion-weighted imaging (DWI). Whole kidney and cortical T1 values were greater in patients than healthy controls (p=0.018 and p<0.0001, respectively), whereas whole kidney, cortical, and medullary DWI ADC values were lower in patients than healthy controls (p=0.017, whole kidney). No differences in T2 or stiffness measurements between the two groups were observed.
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