Meeting Banner
Abstract #0576

Identifying functional correlations between lateral hypothalamus and cingulate cortex underlying brain state-dependent pupil dynamics

Kengo Takahashi1,2, Filip Sobczak1,2, Patricia Pais-Roldán3, and Xin Yu1,4
1High-field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 2Graduate Training Centre of Neuroscience, Tübingen, Germany, 3Institute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich, Jülich, Germany, 4Athinoula A. Martinos Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States

The lateral hypothalamus (LH) is known to mediate different vigilance states and modulate pupil dilation through various neural populations. However, measuring subcortical neuronal activity non-invasively while assessing the brain state has remained challenging. Recently, it has been shown that the coupling between fMRI brain signals and pupil size fluctuations depends on the underlying brain state. In this work, we suggest that the synchronization of LH fMRI signals with pupil fluctuations may indicate modulation of the vigilance level of the brain.

This abstract and the presentation materials are available to members only; a login is required.

Join Here