Abstract #0688

Single-shot model-based non-rigid motion-corrected T1 rho mapping for endogenous assessment of myocardial injury

Aurelien Bustin^1,2,3, Soumaya Sridi², Solenn Toupin⁴, Jerome Yerly^3,5, Davide Piccini^3,6, Ruud B van Heeswijk³, Pierre Jaïs^1,7, Hubert Cochet^1,2, and Matthias Stuber^1,3,5

¹IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, Bordeaux, France, ²Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux, France, ³Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁴Siemens Healthcare France, Saint-Denis, France, ⁵Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, ⁶Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, ⁷Department of Cardiac Electrophysiology, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux, France

Magnetic resonance T1 rho mapping may detect myocardial injuries without the need for exogenous contrast agents. However, multiple and differently T1 rho weighted co-registered acquisitions are required, and the lack of robust motion correction limits its clinical translation. This study introduces a novel automated model-based non-rigid motion correction technique for myocardial T1 rho mapping that makes use of the known signal model to drive the motion correction process. The performance, efficiency and clinical feasibility of the developed framework was investigated prospectively in a cohort of 30 patients with a broad range of ischemic and non-ischemic cardiomyopathies.

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