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Abstract #0688

Single-shot model-based non-rigid motion-corrected T1 rho mapping for endogenous assessment of myocardial injury

Aurelien Bustin1,2,3, Soumaya Sridi2, Solenn Toupin4, Jerome Yerly3,5, Davide Piccini3,6, Ruud B van Heeswijk3, Pierre Jaïs1,7, Hubert Cochet1,2, and Matthias Stuber1,3,5
1IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, Bordeaux, France, 2Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux, France, 3Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 4Siemens Healthcare France, Saint-Denis, France, 5Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, 6Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, 7Department of Cardiac Electrophysiology, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux, France

Magnetic resonance T1 rho mapping may detect myocardial injuries without the need for exogenous contrast agents. However, multiple and differently T1 rho weighted co-registered acquisitions are required, and the lack of robust motion correction limits its clinical translation. This study introduces a novel automated model-based non-rigid motion correction technique for myocardial T1 rho mapping that makes use of the known signal model to drive the motion correction process. The performance, efficiency and clinical feasibility of the developed framework was investigated prospectively in a cohort of 30 patients with a broad range of ischemic and non-ischemic cardiomyopathies.

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