3D myelin imaging using inhomogeneous magnetization transfer (ihMT) has seen increased interest as sequence implementations evolve. This has mostly been based on prepared or pseudo-steady-state gradient echo sequences. However, Fast-Spin-Echo (FSE) sequences should have a theoretical SNR advantage over GRE. Here we report implementation of a CSF-suppressed FSE sequence for ihMT imaging (FLAIR-ihMT), exploring through simulations the effect of CSF suppression and providing first imaging results, highlighting the benefits of CSF suppression, potential for whole brain high-resolution imaging and translation down to the spinal cord.
This abstract and the presentation materials are available to members only; a login is required.