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Abstract #0775

3D APTw Brain Tumor Imaging with Compressed SENSE: Comparison of Different Acceleration Factors and with Conventional Parallel Imaging

Nan Zhang1, Qingwei Song2, Ailian Liu2, Haonan Zhang2, Renwang Pu2, Jiazheng Wang3, and Zhiwei Shen3
1The First Affilliated Hospital of Dalian Medical University, Dalian, China, 2The First Affiliated Hospital of Dalian Medical University, Dalian, China, 3Philips Healthcare, Beijing, China, Beijing, China

Amide proton transfer weighted (APTw) imaging is a novel and promising MRI method for brain tumor imaging, but it can be time-consuming. Common parallel imaging methods, like SENSE, can lead to reduced image quality and increased artifact at high acceleration factors. Here, the compressed SENSE (CS) technique with combined strength from both compressed sensing and SENSE was evaluated for the acceleration of APTw imaging in brain. Results showed that it is feasible to apply an CS accelerator factor of 5 to APTw imaging of brain tissue and tumor, which could reduce the scan time to less than 1 min.

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