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Abstract #0792

Preconditioned water–fat total field inversion: application to spine quantitative susceptibility mapping (QSM)

Christof Boehm1, Nico Sollmann2,3,4, Jakob Meineke5, Sophia Kronthaler1, Stefan Ruschke1, Michael Dieckmeyer2,3, Kilian Weiss6, Claus Zimmer2,3, Marcus R. Makowski1, Thomas Baum2,3, and Dimitrios C. Karampinos1
1Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany, 2Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany, 3TUM-Neuroimaging Center, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany, 4Department of Diagnostic and Interventional Radiology, University Hospital Ulm, Ulm, Germany, 5Philips Research Lab, Hamburg, Germany, 6Philips Healthcare, Hamburg, Germany

Body-QSM remains challenging for various reasons including, (a) the incomplete separation of background- and local-fields included by assumed approximations,(b) incorrect modeling at low-SNR-voxels included by linear modeling of the inverse problem and (c) streaking artifacts. A recently developed total-field-inversion (TFI) QSM method that directly estimates the susceptibility from multi-echo data showed significant alleviation of the above artifacts. However, the original TFI method can only be applied to regions with one species. This work proposes a QSM method that directly estimates susceptibility from multi-echo data in regions where water and fat are present and demonstrates its advantages over former proposed methods.

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