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Abstract #0795

QSM of the head-and-neck at 7T using simultaneous fat-water imaging with SMURF

Beata Bachrata1,2, Korbinian Eckstein1, Siegfried Trattnig1,2, and Simon Daniel Robinson1,3,4
1High Field MR Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria, 2Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, 3Centre of Advanced Imaging, University of Queensland, Brisbane, Australia, 4Department of Neurology, Medical University of Graz, Graz, Austria

We address the challenges of QSM in regions outside of the brain which contain disconnected structures - leading to difficulty in masking - and significant amounts of fat with chemical shift and relaxation differences relative to water - leading to errors in susceptibility estimates. We propose a mask generation approach based on signal phase and show that the errors in susceptibility estimates can be eliminated using simultaneous fat-water imaging with SMURF. Using multi-echo acquisition and inverse-variance-weighted echo combination, we generate high CNR, chemical shift and relaxation effects-free susceptibility maps of the head-and-neck at 7T.

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