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Abstract #0796

QSMART: a parallel stage QSM pipeline for suppression of cortical and venous artifacts

Negin Yaghmaie1,2, Warda Syeda3,4, Chengchuan Wu1,2, Yicheng Zhang1,2, Bradford A. Moffat1,4, Rebecca Glarin1,5, Scott Kolbe4,6,7, and Leigh Johnston1,2
1Melbourne Brain Centre Imaging Unit, The University of Melbourne, Melbourne, Australia, 2Department of Biomedical Engineering, The University of Melbourne, Melbourne, Australia, 3Melbourne Neuropsychiatry Centre, The University of Melbourne, Melbourne, Australia, 4Department of Medicine and Radiology, The University of Melbourne, Melbourne, Australia, 5Department of Radiology, Royal Melbourne Hospital, Melbourne, Australia, 6Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Australia, 7Department of Radiology, Alfred Hospital, Melbourne, Australia

We propose a two-stage QSM method, Quantitative Susceptibility Mapping Artifact Reduction Technique (QSMART), in which tissue and vein susceptibility values are estimated in parallel by generating a vasculature mask from the magnitude data using a Frangi filter. Spatially Dependent Filtering is employed for the background field removal and the two susceptibility estimates are combined in the final QSM map. QSMART is compared to RESHARP/iLSQR and V-SHARP/iLSQR inversion on 7T in vivo single and multiple-orientation scans. QSMART demonstrates superior artifact suppression in the cortex and near vasculature, and is a robust tool for susceptibility estimation. QSMART code is available at

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