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Abstract #0876

Functional Reorganization associated with Language Recovery after Repetitive Transcranial Magnetic Stimulation in Chronic Aphasic Stroke

Bing-Fong Lin1, Po-Yi Tsai2, and Chia-Feng Lu1
1Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan, 2Physical Medicine and Rehabilitation, Taipei Veterans General Hospital, Taipei, Taiwan

Low-frequency repetitive transcranial magnetic stimulation (rTMS) provided promising results to facilitate the language recovery in stroke patients with non-fluent aphasia. This study demonstrated that the contralesional inhibitory rTMS treatment can induce the functional reorganization within language networks and recovery of language function in chronic aphasic stroke. The correlation analysis further revealed the association between altered functional connectivity and improved language ability after rTMS treatment. Finally, we reported that the involved functional circuits for the language recovery may depend on lesion location and size of stroke.

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