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Abstract #0995

Myocardial T1 mapping and feature tracking in patients with OSA: potential novel insights into adaptive left ventricular remodeling phase

Xiaobin Zhou1, Xiaoyu Wei1, Yingjie Mei2, Qiong Ou3, Zhecheng Du4, and Hui Liu1
1Department of Radiology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China, 2Philips Healthcare, Guangzhou, China, 3Sleep Center, Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, China, 4Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China

The comprehensive assessment of left ventricular (LV) remodeling by cardiac magnetic resonance (CMR) imaging with T1 mapping and feature tracking (FT) technology in obstructive sleep apnea (OSA) was conducted in this study. Indexed extracellular volume (iECV) and indexed cellular volume (iCV) of myocardial tissue construction were derived from T1 mapping. The results show that elevated LV mass index (LVMi) in OSA was mainly from iCV, while not from iECV, with no LV ejection function (LVEF) or strain parameters impairment. Cellular hypertrophy accompanied with normal LV systolic function in patients with OSA may contribute to adaptive LV remodeling phase.

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Abstract