3D MRE allows volumetric assessment of liver stiffness. Performance of this method as compared to 2D techniques (GRE and seEPI), was evaluated, with respect to the ROI areas per slice, stiffness values, and presence of artifacts. The 3D MRE provided larger area of liver and was less prone to artifacts. Liver Stiffness Measures (LSM) based on 3D technique were lower than 2D technique. 3D MRE exhibits less susceptibility to artifacts and provides larger measurable areas of liver. LSM based on 3D MRE however were lower than 2D techniques.