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Abstract #1029

Short echo time dual-frequency MR Elastography with Optimal Control RF pulses

Pilar Sango Solanas1, Kevin Tse Ve Koon1, Eric Van Reeth1,2, Cyrielle Caussy3,4, and Olivier Beuf1
1Univ Lyon, INSA‐Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1206, F‐69616, Lyon, France, 2CPE Lyon, Département Sciences du Numérique, Lyon, France, 3Univ Lyon, Laboratoire CarMen, Inserm, INRAe, INSA Lyon, Université Claude Bernard Lyon 1, Pierre-Bénite, France, 4Hospices Civils de Lyon, Département Endocrinologie, Diabète et Nutrition, Hôpital Lyon Sud, Pierre-Bénite, France

Magnetic Resonance Elastography (MRE) quantifies the mechanical properties of tissues, typically applying motion encoding gradients (MEG). High frequencies are difficult to reach due to slew rate limitations and low frequencies induce too long TEs, yielding magnitude images with low SNR. Multifrequency results allow better characterizations of tissues using data usually acquired through sequential monofrequency experiments. In this study, we generate optimal control-based RF pulses to outperform simultaneous multifrequency MRE. The pulse is applied with a constant gradient during the mechanical excitation to simultaneously achieve spatially selective excitation and motion encoding. Results on phantom demonstrated the feasibility of the proposed method.

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