Abstract #1030

Comparative analysis of indentation and magnetic resonance elastography for measuring viscoelastic properties

Yu Chen¹, Suhao Qiu¹, Zhao He¹, Fuhua Yan², Ruokun Li², and Yuan Feng¹

¹Institute for Medical Imaging Technology, School of Biomedical Engineering, Shanghai Jiao Tog University, Shanghai, China, ²Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Comparing viscoelastic properties of soft tissues measured in vivo and ex vivo are of interests for basic science and clinical translation. Magnetic resonance elastography (MRE) and indentation are two commonly used techniques for measurement of tissue viscoelasticity. In this study, we used a gelatin phantom to compare measurements by MRE and indentation. Using 2nd-order Prony series, frequency response measured from indentation was estimated. We observed apparent frequency-dependent behaviors from MRE in the range of 50-100 Hz, but not from indentation. Results implied that MRE and indentation measures at different frequency ranges.

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