In this study, we used multi-excitation MR elastography (MRE) in conjunction with transversely isotropic NLI (TI-NLI) to estimate the anisotropic viscoelastic parameters of the human brain. We collected data on ten subjects and took averages of the parameters within individual regions of the brain. Through comparison of regions of interest, we found significant differences between the parameter estimate of gray matter and white matter and between individual white matter tracts. The results of this study indicate that multi-excitation MRE and TI-NLI can generate consistent anisotropic parameter estimates for WM that capture innate differences in individual tract structure.
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