Meeting Banner
Abstract #1040

Brain Function in Obesity: A Pilot Study to Assess Effects of Bariatric Surgery

Nareen Anwar1, Wesley J Tucker2, Nancy Puzziferri3, Jake Samuel2, Vlad G Zaha3, Ildiko Lingvay3, Jaime Almandoz3, Jing Wang2, Edward A Gonzales2, Matthew Brothers2, Michael Douglas Nelson2, and Binu P Thomas2,3
1The University of Texas at Dallas, Richardson, TX, United States, 2The University of Texas at Arlington, Arlington, TX, United States, 3University of Texas Southwestern Medical Center, Dallas, TX, United States

Obesity is an ongoing epidemic that is associated with cognitive dysfunction and is a prominent precursor to a variety of neurogenerative diseases. Bariatric surgery is an effective and long-term weight loss strategy that can improve neurocognitive function. However, the mechanisms that drive these improvements are unknown. In this study, magnetic resonance imaging (MRI) is utilized to assess changes in cerebral metabolic rate of oxygen (CMRO2) levels in bariatric surgery candidates before and after their surgery. These values are compared with normal healthy weight controls of a similar age and reassessed after 2 weeks and 14 weeks.

This abstract and the presentation materials are available to members only; a login is required.

Join Here