Due to a shortage of transplantable lungs, careful preservation of viable donor lungs is of paramount importance. Ex-Vivo Lung Perfusion (EVLP) and cold static storage are two clinical techniques used to preserve donor lungs prior to transplantation. In this study, magnetic resonance spectroscopy was used to compare the ability of un-ventilated normothermic EVLP vs. cold static storage to preserve rat lungs’ ATP energy status over a 5-hour ischemic period. The EVLP model was slightly better than cold static storage at sustaining the lungs’ ATP.
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