We propose a new sequence called MIXTURE (Multi-Interleaved X-prepared TSE with inTUitive RElaxometry). MIXTURE based is a 3D TSE that can set arbitrary echo times using the T2 preparation pulses, and enables several image contrasts (such as PDW, T2W) and T2 mapping by acquiring at least two echo time images. MIXTURE could simultaneously provide morphology, pathology and T2 quantitative lumbar imaging in one single scan. This sequence is very promising to evaluate the degeneration of nerve roots and intervertebral disc for 3D T2 mapping and improve the ability of diagnostic imaging around the lumbar for 3D multi contrast MRI.
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