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Abstract #1340

Quantitative Accuracy of Diffusion-Weighted Imaging Techniques as a Function of Susceptibility Artifact Resilience

Volkan Emre Arpinar1,2, Alexander D Cohen1, Sampada Bhave3, and Kevin M Koch1,2
1Radiology, Medical College of Wisconsin, Milwaukee, WI, United States, 2Center for Imaging Research, Medical College of Wisconsin, Milwaukee, WI, United States, 3Canon Medical Research USA, Cleveland, OH, United States

Diffusion weighted imaging(DWI) is a workhorse sequence for many clinical and research applications of MRI. Beyond the role in neuroimaging, DWI has also been deployed for use other anatomies outside the head. However, in some anatomies with air-tissue susceptibility boundaries or proximity to metallic implants, DWI assessment may be challenging due to substantial susceptibility artifacts. In this study, the diffusion quantification accuracy of several DWI sequences within increasing resilience to susceptibility artifacts were compared using an established DWI phantom. In addition, a controlled test of two sequences with substantial differences in susceptibility artifact reduction was performed on spinal cord DWI.

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