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Abstract #1477

High Resolution Adiabatic T1ρ Mapping Using 3D MAPSS Sequence at 3T

Can Wu1,2 and Qi Peng3
1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 2Philips Healthcare, Andover, MA, United States, 3Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, United States

The 3D MAPSS T1ρ sequence provides fast and accurate T1ρ quantification with high spatial fidelity using RF phase cycling and variable flip angle in a MP-GRE sequence. However, the conventional 3D MAPSS sequence uses continuous-wave RF pulses for spin locking and is thus sensitive to B0 and B1 field inhomogeneities. In this study, a 3D MAPSS T1ρ sequence with adiabatic RF pulses was implemented and was shown to be less sensitive to B0 frequency offset on phantom compared to conventional 3D MAPSS T1ρ mapping. It was also successfully applied to high-resolution 3D T1ρ mapping of knee cartilage and brain tissue.

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