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Abstract #1488

Glutamine contribution to GluCEST at 7.0T

Ravi Prakash Reddy Nanga1, Mohammad Haris2, Hari Hariharan1, and Ravinder Reddy1
1Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2Research Branch, Sidra Medical and Research Center, Doha, Qatar

Glutamate chemical exchange saturation transfer (GluCEST) is an emerging imaging technique and in the recent years has shown promising applications in Alzheimer’s, Parkinson’s, Epilepsy, Brain tumors and Schizophrenia. Due to structural similarity of glutamine with glutamate, often there is a misconception of glutamine contribution to CEST effect of glutamate. In this study, we investigated the glutamine contribution to glutamate CEST at 3ppm offset.

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