Abstract #1659

Morphological changes of the corpus callosum in antipsychotic-naive first-episode schizophrenia before and 1-year after treatment

Bo tao¹, Yuan Xiao¹, Wenjing Zhang¹, Na Hu¹, John A Sweeney^1,2, and Su Lui¹

¹Huaxi MR Research Center (HMRRC), Functional and molecular imaging Key Laboratory of Sichuan Province, Department of Radiology, West China Hospital of Sichuan University, Chengdu, China, ²Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, Cincinnati, OH, United States

The present study demonstrates deficits of the callosal morphology in schizophrenia, which may reflect an neurodevelopment aberration. And short-term antipsychotics may not have a significant impact on the CC morphology in the early stage of illness.

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