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Abstract #1792

Accuracy of quantified 23Na MRI in ischemic Stroke with varying undersampling Factors and CNN Postprocessing

Anne Adlung1, Nadia Karina Paschke1, Alena-Kathrin Golla1,2, Dominik Bauer1,2, Sherif Mohamed3, Melina Samartzi4, Marc Fatar4, Eva Neumaier Probst3, Frank Gerrit Zöllner1,2, and Lothar Rudi Schad1
1Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 2Mannheim Institute for Intelligent System in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 3Department of Neuroradiology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 4Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

This study investigates factors of k-space undersampling for which CNN postprocessing is able to improve 23Na MRI data. Data from 53 patients with ischemic stroke was included and image reconstruction was performed with full k-space data (FI) and with k-space data that was reduced (RI) by different factors (S = 2, 4, 5 and 10). Postprocessing with a convolutional neural network was applied to the highly undersampled 23Na MRI data. The CNN was able to significantly improve SNR and SSIM for all S with both loss functions. CNN postprocessing could enable significant reduction of 23Na MRI data acquisition time.

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