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Abstract #1803

Low field 19F imaging of perfluoroctylbromide: eliminating chemical shift effects and minimizing scalar coupling signal loss

Javad Parsa1 and Andrew Webb1
1Leiden University Medical Center, Leiden, Netherlands

Phantom 19F images have been obtained from perflurooctylbromide (PFOB) at very low magnetic field (2.15 MHz). The small spectral dispersion (in Hz) means that all fluorine nuclei contribute to the signal without chemical shift artifacts or the need for specialized sequences. Long turbo spin echo trains with short interpulse intervals and full 180o refocussing pulses suppress scalar coupling, leading to long apparent T2 values and highly efficient data collection. Overall, the detection efficiency of PFOB is actually higher than that of tissue protons at very low field.

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