Abstract #1821

Kartogenin and synthetic melanin nanoparticle loaded hydrogel scaffold for cartilage regeneration and monitored by quantitative MRI

Chuyao Chen¹, Shaoshan Huang², Zelong Chen¹, Chenggong Yan¹, Yingjie Mei³, Yikai Xu¹, and Rui Guo²

¹Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, ²Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Guangdong Provincial Engineering and Technological Research Centre for Drug Carrier Development, Department of Biomedical Engineering, Jinan University, Guangzhou, China, ³Philips Healthcare, Guangzhou, China

We have developed a KGN/SMNP loaded cell-therapy theranostic hydrogel scaffold for cartilage repair. The multifunctional hydrogel system is expected to be a tissue engineering strategy for cartilage regeneration and non-invasive monitoring by multiparametric MR imaging.

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