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Abstract #1821

Kartogenin and synthetic melanin nanoparticle loaded hydrogel scaffold for cartilage regeneration and monitored by quantitative MRI

Chuyao Chen1, Shaoshan Huang2, Zelong Chen1, Chenggong Yan1, Yingjie Mei3, Yikai Xu1, and Rui Guo2
1Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, 2Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Guangdong Provincial Engineering and Technological Research Centre for Drug Carrier Development, Department of Biomedical Engineering, Jinan University, Guangzhou, China, 3Philips Healthcare, Guangzhou, China

We have developed a KGN/SMNP loaded cell-therapy theranostic hydrogel scaffold for cartilage repair. The multifunctional hydrogel system is expected to be a tissue engineering strategy for cartilage regeneration and non-invasive monitoring by multiparametric MR imaging.

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