Meeting Banner
Abstract #1824

The Effect of Transmit B1 Inhomogeneity on Hyperpolarized [1-13C]-Pyruvate Metabolic MR Imaging Biomarkers

Collin J. Harlan1, Zhan Xu1, Christopher M. Walker1, Keith A. Michel1, Galen D. Reed 2, and James A. Bankson1,3
1Department of Imaging Physics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, United States, 2GE Healthcare, Dallas, TX, United States, 3The University of Texas M.D. Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, TX, United States

Accurate signal excitation is imperative when conducting hyperpolarized 13C MRI studies. It has been determined from previous work that greater than ±10% deviation in excitation angle can lead to significant excitation angle dependent errors in kinetic analysis of HP [1-13C] pyruvate to lactate conversion. This work was conducted to characterize the B1+ field homogeneity of a 13C volume transmit clamshell coil. Furthermore, an assessment of the impact of potential B1+ inhomogeneities on semi-quantitative and quantitative hyperpolarized metabolic MR imaging biomarkers was conducted.

This abstract and the presentation materials are available to members only; a login is required.

Join Here