Accurate signal excitation is imperative when conducting hyperpolarized 13C MRI studies. It has been determined from previous work that greater than ±10% deviation in excitation angle can lead to significant excitation angle dependent errors in kinetic analysis of HP [1-13C] pyruvate to lactate conversion. This work was conducted to characterize the B1+ field homogeneity of a 13C volume transmit clamshell coil. Furthermore, an assessment of the impact of potential B1+ inhomogeneities on semi-quantitative and quantitative hyperpolarized metabolic MR imaging biomarkers was conducted.
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