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Abstract #1825

Simultaneous quantification of T2 and T2* by accelerated 10-echo GESE-EPIK sequence for carrageenan-phantoms and in vivo data

Fabian Küppers1,2,3, Seong Dae Yun1, and N. Jon Shah1,2,4,5
1Institute of Medicine and Neuroscience 4, Forschungszentrum Juelich GmbH, Jülich, Germany, 2Institute of Medicine and Neuroscience 11, Forschungszentrum Juelich GmbH, Jülich, Germany, 3RWTH Aachen University, Aachen, Germany, 4Department of Neurology, RWTH Aachen University, Aachen, Germany, 5JARA - BRAIN - Translational Medicine, Aachen, Germany

Combining GE and SE signals enables quantification of several pertinent parameters making it useful in various applications. An 10-echo GESE sequence based on EPIK, known as EPI with keyhole, has been presented in our earlier work. This work employs an accelerated sequence implementation and aims to perform quantification of T2/T2* for both phantom and in vivo data. The method was configured to provide improved resolution within feasible TEs for brain scans, i.e. 1 minute. The quantified T2/T2* values were in good agreement with values from reference methods. Moreover, an SNR/tSNR analysis proves the signal and time gain from multi-shot acceleration.

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