Abstract #1825

Simultaneous quantification of T2 and T2* by accelerated 10-echo GESE-EPIK sequence for carrageenan-phantoms and in vivo data

Fabian Küppers^1,2,3, Seong Dae Yun¹, and N. Jon Shah^1,2,4,5

¹Institute of Medicine and Neuroscience 4, Forschungszentrum Juelich GmbH, Jülich, Germany, ²Institute of Medicine and Neuroscience 11, Forschungszentrum Juelich GmbH, Jülich, Germany, ³RWTH Aachen University, Aachen, Germany, ⁴Department of Neurology, RWTH Aachen University, Aachen, Germany, ⁵JARA - BRAIN - Translational Medicine, Aachen, Germany

Combining GE and SE signals enables quantification of several pertinent parameters making it useful in various applications. An 10-echo GESE sequence based on EPIK, known as EPI with keyhole, has been presented in our earlier work. This work employs an accelerated sequence implementation and aims to perform quantification of T₂/T₂* for both phantom and in vivo data. The method was configured to provide improved resolution within feasible TEs for brain scans, i.e. 1 minute. The quantified T₂/T₂* values were in good agreement with values from reference methods. Moreover, an SNR/tSNR analysis proves the signal and time gain from multi-shot acceleration.

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