We proposed a CEST imaging method using compressed sensing to accelerate image acquisition. Compared with the full sampled one with two averages, the compressed sensing method used only 7.6% scan time with around 0.5% error in amide proton transfer weighted (APTw) images. The whole-brain acquisition for one RF offset took only 6 seconds. This method can accelerate conventional APTw images to reduce motion artifact and make a high signal-to-noise ratio acquisition with large number offsets for Lorentzian fitting possible.
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