Abstract #1873

The Effect of Hepatic Fat on T2 of water signal in single voxel multi-echo MRS and fat-suppressed radial TSE T2 mapping.

Diana Bencikova^1,2, Marcus Raudner¹, Sarah Poetter-Lang¹, Nina Bastati¹, Ahmed Ba-Ssalamah¹, Siegfried Trattnig^1,2, and Martin Krššák^2,3

¹Department of Radiology, Medical University Vienna, Vienna, Austria, ²Christian Doppler Laboratory for Clinical Molecular Imaging, MOLIMA, Vienna, Austria, ³Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria

MRI-based T₂ mapping was suggested for the grading of hepatic parenchyma inflammation. Studies using multi-echo MRS suggest the effect of hepatic fat accumulation on T₂ values of the water signal. Here, we analyzed the effect of hepatic fat fraction on water T₂s in phantoms and patients in vivo with MRS and T₂ mapping based on fast radial turbo-spin-echo acquisition with fat saturation. While there was an effect in phantoms of low FF, in the population of patients with FF up to 15%, no significant influence could be observed.

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