The increasing use of MR elastography (MRE) for the quantification of liver fibrosis and inflammation demands a rapid and accurate 3D MRE sequence. 3D MRE usually requires multiple breath-holds, which prolongs acquisition times and introduces misalignment between the different acquisitions. We propose Intenso, a novel GRE-MRE sequence that enables 3D motion-encoding for volumetric MRE of the liver in a single breath-hold. The sequence combines simultaneous multi-slice excitation (SMS), Hadamard motion encoding and a multi-shot GRE-MRE sequence resulting in a total acquisition time of 17 seconds. In-vivo results are shown in three healthy volunteers and compared to a well-established GRE-MRE sequence.
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