Presbycusis (PC) is a gradually progressive bilateral symmetrical sensory-neural hearing loss, characterized by hearing loss at high frequencies. As the most common sensory deficit in older adults, hearing deprivation was proved to be the independent influencing factor of dementia. However, the exact pathophysiological mechanism of PC and its relationship with cognitive impairment is largely unknown. In this study, therefore, we applied an ICA-based resting-state networks (RSNs) analysis to examine changes in functional connectivity of intra- and inter-network in patients with PC. Then, we explore the relationship between these abnormal functional connectivity and cognitive impairments in PC patients.
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