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Abstract #1935

The changes of hippocampus in Type 2 Diabetes Mellitus Patients with Mild Cognitive Impairment: A Multiple Advanced Diffusion Models study

Mengzhu Wang1, Yunzhu Wu1, and Wenjiao Lyu2
1MR Scientific Marketing, Siemens Healthcare, Guangzhou, China, 2Department of Radiology, the First Affiliated Hospital of Guangzhou University, Guangzhou, China

The aim of this study was to elucidate a multiple diffusion-model-based radiomics model in detecting the changes of hippocampus in Type 2 Diabetes Mellitus Patients with Mild Cognitive Impairment. We used diffusion features derived from DTI, DKI, NODDI and MAP-MRI models and chose LR as the classifier to construct a prediction model. The results showed that the most accurate prediction was achieved by incorporating the NODDI_ICVF and MAP_NG into a nomogram, with AUC and accuracy reached 0.80 and 0.78.

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