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Abstract #2394

Retrospective Cardiac Gating of Simultaneous Coherent/Incoherent Motion Imaging (SCIMI) in the Brain

Isabelle Heukensfeldt Jansen1, Luca Marinelli1, J Kevin DeMarco2, Robert Y Shih2,3, Vincent B Ho2,3, and Thomas TK Foo1
1GE Global Research Center, Niskayuna, NY, United States, 2Walter Reed National Military Medical Center, Bethesda, MD, United States, 3Uniformed Services University of the Health Sciences, Bethesda, MD, United States

We use retrospective cardiac gating with phase-sensitive reconstruction of diffusion tensor data to create a 4D profile of motion in brain parenchyma with velocity encoding value (VENC) of 0.18 mm/s. We imaged the brain of a healthy volunteer in regions surrounding the ventricles with synchronized recording of a PPG signal. We created a velocity profile for the volume spanning the full cardiac cycle by binning individual images according to the local cardiac phase. Results show coherent periodic motion with distinct systolic/diastolic phases. This motion is thought to comprise of both tissue movement and interstitial fluid flow (ISF) in the region.

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