We use retrospective cardiac gating with phase-sensitive reconstruction of diffusion tensor data to create a 4D profile of motion in brain parenchyma with velocity encoding value (VENC) of 0.18 mm/s. We imaged the brain of a healthy volunteer in regions surrounding the ventricles with synchronized recording of a PPG signal. We created a velocity profile for the volume spanning the full cardiac cycle by binning individual images according to the local cardiac phase. Results show coherent periodic motion with distinct systolic/diastolic phases. This motion is thought to comprise of both tissue movement and interstitial fluid flow (ISF) in the region.
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