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Abstract #2467

Application of DKI and IVIM in staging of hepatic fibrosis

YANLI JIANG1, Jie Zou1, FengXian Fan1, Yuping Bai1, Jing Zhang1, and Shaoyu Wang2
1Department of Magnetic Resonance, LanZhou University Second Hospital, LanZhou, China, 2MR Scientific Marketing, Siemens Healthineers, Shanghai, China

Intravoxel Incoherent Motion (IVIM) is a MRI method that enables simultaneous assessment of diffusion and perfusion. Diffusion Kurtosis imaging (DKI) is based on a mathematical approach that uses a polynomial model with a dimensionless factor called the kurtosis (K). This study evaluated the relationship between IVIM-DKI diffusion models and clinical-pathologic to assess their diagnostic accuracy for staging of hepatic fibrosis. We found that a high level of hepatic fibrosis usually have a higher MK values. A significant negative correlation was observed between FibroScan and MD. In conclusion, compared with IVIM, DKI might be more useful in staging of hepatic fibrosis.

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