Abstract #2547

MRI enhancement of TPP-TEMPOL during reduces kidney damage

Quan Tao¹, Peiwei Yi¹, Zimeng Cai¹, Yingjie Mei², Ruiyuan Liu¹, and Yanqiu Feng¹

¹School of Biomedical Engineering, Southern Medical University, Guangzhou, China, ²Philips healthcare, Guangzhou, China

In this study, we synthesis a mitochondria-targeted contrast agent named triphenylphosphine-2,2,6,6-tetramethylpiperidine-1-oxyl (TPP-TEMPOL) to protect the kidney from the damage induced by rhabdomyolysis. At the same time, measured the T1 changes by MRI.

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