We used clinical high resolution 3T MRI to investigate brain ventricle changes over time in patients with clinically isolated syndrome (CIS) who are at the early stages of disease, which may eventually become multiple sclerosis. While most patients showed an overall increase in ventricle volume, 23% also showed contractions greater than the range of variation in healthy subjects, even over a period of years. Patients with contracting ventricles were significantly younger than those without. This suggests that, in addition to neurodegeneration, other processes are implicated that lead to a transient enlargement of the ventricles, which then later resolves.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords