Experience induced visual cortical (VC) plasticity is key for adequate pathway maturation and circuitry refinement. Competing inputs from each eye arriving to the thalamic lateral geniculate nucleus and, later, to VC, are necessary to shape and develop visual binocularity. Without such competition, an increased responsiveness and number of binocular cortical neurons has been reported. Here, we investigated monocular stimulation in rats that had been dark reared and compared their cortical BOLD responses with normal reared animals. Increased BOLD responses appeared along the VC of the dark reared group, suggesting a lack of pathway maturation and binocular integration.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords