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Abstract #2949

The value of T2 mapping to characterize early knee joint cartilage damage in hemophilia arthropathy

Shufang Wei1, Jiajia Li1, Xianchang Zhang2, Jing An3, and Yinghui Ge1
1Fuwai Central China Cardiovascular Hospital, Zhengzhou, China, 2MR Collaboration, Siemens Healthcare Ltd, Beijing, China, 3Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China

Detecting early articular cartilage damage can help formulate preventive treatment plans for hemophilia arthropathy (HA). Magnetic responance imaging (MRI) T2 mapping has been used extensively to investigate early chondral changes in osteoarthritis; however, it has seldomly been applied to investigate HA. This study acquired T2-mapping results on 30 patients (54 knees) with HA and 15 volunteers (24 knees). Patients with HA had significantly higher knee cartilage T2 values than the healthy controls. The T2 values also increased with the disease severity, suggesting that MRI T2 mapping is a promising method for detecting early stage cartilage damage in patients with hemophilia.

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