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Abstract #3011

Evaluating normative Cerebellum radiomics on FLAIR images

Umang Pandey1, Jitender Saini2, Manoj Kumar2, Rakesh Gupta3, and Madhura Ingalhalika1
1Symbiosis Centre for Medical Image Analysis, Symbiosis International University, Pune, India, 2Department of Radiology, National Institute of Mental Health and Neurosciences, Bengaluru, India, 3Department of Radiology,Fortis Memorial Research Institute, Gurgaon, India

Radiomics in neuroimaging has gained momentum as a noninvasive prediction tool not only to differentiate between types of brain tumors, but also to create phenotypic signatures in neurological/neuropsychiatric disorders. However, there is currently little understating about the robustness and reproducibility of radiomic features in a baseline normative population. Moreover, the radiomics across cerebellum which has a more complex anatomy has not been evaluated This study investigates and demonstrates the intra- and inter-scanner reproducibility and the spatial variations within the regions of the cerebrum and cerebellum. Our findings suggest that care must be taken while interpreting these features for pathological inferences.

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