The MNI PD25 subcortical atlas, which consists of key structures involved in Parkinson’s disease, was automatically segmented on each 3T control and Parkinson’s disease diffusion data obtained from the Parkinson’s disease Progression Marker Initiative (PPMI) database. Diffusion measures such as FA, AD, RD, MD and QA were obtained from each segmented ROI and interconnectivity for comparison between controls and Parkinson’s disease patients to observe for significant biomarkers that occur in basal ganglia due to Parkinson’s disease.
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