This study aimed to explore the changes of amplitude low-frequency fluctuation (ALFF) values nearly one-year before and after abstinence in patients with Methamphetamine Abstinence (MA), and to investigate potential imaging markers related to withdrawal based on Harvard-Oxford Atlas. Compared with short-term abstinence group, right middle frontal gyrus (8) and right inferior frontal gyrus, pars triangularis (10) had significantly higher ALFF value at long-term abstinence group. The ALFF value of the two regions may be a new biomarker which can reflect the impact of withdrawal on brain function.
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