Different treatments were not given to patients HRCT on diagnosis of atypical interstitial pneumonia appears to be powerless, so further examination of pathological biopsy is usually required. However, pathological biopsy often causes a series of complications and reduces the survival rate of patients. This study aims to distinguish between UIP and NSIP using MRI dynamic enhancement quantitative parameters. The results showed that the blood flow in the lungs of UIP patients is significantly reduced. The quantitative parameters of MRI dynamic enhancement had potential in distinguishing UIP from NSIP.