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Abstract #3217

Lung parenchyma T1 mapping correlates lung pathology seen on CT in patients with pulmonary hypertension.

Laura Saunders1, Dave Capener1, David G Kiely1,2, Andy J Swift1, and Jim M Wild1
1Infection Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom, 2Sheffield Pulmonary Vascular Disease Unit, Sheffield, United Kingdom

Assessment of lung changes in patients with pulmonary hypertension plays an important role in establishing patient aetiology and treatment. 82 patients with suspected pulmonary hypertension underwent 2D single slice Look-Locker inversion recovery T1 mapping. Lung T1 was significantly lower in patients with emphysema seen on 3D CT than in patients with fibrosis, centrilobular ground glass or no lung disease seen on 3D CT. Lung T1 was more sensitive in differentiating lung pathology seen on CT when excluding lung vessels from average metrics, and when using median rather than mean lung T1.

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