We have previously shown the advantages of multi- over single-breath imaging of lung ventilation using HP gas MRI, and have recently introduced our approach for comprehensively assessing the lung function during a tidal breathing scheme to quantify ventilation and dissolved parameters of xenon distribution. Here, we presented the repeatability of the imaging markers in a healthy subject and a patient with severe chronic obstructive pulmonary disease (COPD) with persisting cough. We have shown that the technical back-to-back reproducibility of measuring lung function with our scheme is excellent in a healthy subject and satisfactory in a COPD subject with persisting cough.
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