3D isotropic images of hyperpolarized 129Xe dissolved in the brain were acquired with 1 L of inhaled xenon gas dose using a density-weighted MR spectroscopic imaging method. Images were acquired from 2 healthy male volunteers. The data was acquired with a voxel size of (2cm)3 and reconstructed to a voxel size of (0.625 cm)3 through zero filling. The isotropic voxel size and the high spectral resolution surpass previous reports using conventional 2D and echo planar spectroscopic imaging methods.
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