Abstract #3585

In Vivo T2* of Hyperpolarized 13C-Metabolites in Human Brain, Heart, Kidney, and Spleen: An Imaging Approach

Junjie Ma¹, Crystal E. Harrison¹, James Ratnakar¹, Galen D. Reed², Rolf F. Schulte³, Vlad G. Zaha^1,4, Craig R. Malloy^1,4,5, and Jae Mo Park^1,5,6

¹Advanced Imaging Research Center, UT SOUTHWESTERN MEDICAL CENTER, Dallas, TX, United States, ²GE Healthcare, Dallas, TX, United States, ³GE Healthcare, Munich, Germany, ⁴Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States, ⁵Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ⁶Electrical and Computer Engineering, UT Dallas, Richardson, TX, United States

Multi-echo ¹³C spiral imaging sequence combined with a spectral-spatial radiofrequency pulse can measure T₂* of ¹³C-labeled metabolite signals in vivo. In this study, we measured T₂*s of hyperpolarized [1-¹³C]pyruvate and products in human heart, brain, kidney and spleen.

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