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Abstract #3585

In Vivo T2* of Hyperpolarized 13C-Metabolites in Human Brain, Heart, Kidney, and Spleen: An Imaging Approach

Junjie Ma1, Crystal E. Harrison1, James Ratnakar1, Galen D. Reed2, Rolf F. Schulte3, Vlad G. Zaha1,4, Craig R. Malloy1,4,5, and Jae Mo Park1,5,6
1Advanced Imaging Research Center, UT SOUTHWESTERN MEDICAL CENTER, Dallas, TX, United States, 2GE Healthcare, Dallas, TX, United States, 3GE Healthcare, Munich, Germany, 4Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States, 5Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 6Electrical and Computer Engineering, UT Dallas, Richardson, TX, United States

Multi-echo 13C spiral imaging sequence combined with a spectral-spatial radiofrequency pulse can measure T2* of 13C-labeled metabolite signals in vivo. In this study, we measured T2*s of hyperpolarized [1-13C]pyruvate and products in human heart, brain, kidney and spleen.

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