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Abstract #3703

The value of Amide Proton Transfer weighted and Dynamic Contrast-Enhanced imaging in peritumoral edema assisted grading of gliomas

Xinying Ren1, Yujing Li1, Rui Wang1, Tao Wen1, Diaohan Xiong1, Pengfei Wang1, Guangyao Liu1, Jing Zhang1, and Kai Ai2
1Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China, 2Philips Healthcare, Xi'an, China

The study was to quantitatively analyze the peritumoral infiltration assisted gliomas grading by using amide proton transfer (APT) and dynamic contrast-enhanced imaging (DCE). Although many scholars use APT and DCE to help grading gliomas, but few of them pay attention to the peritumoral area. This research investigated the relationship between APT and DCE based Ktrans value in peritumoral. The results show that these two parameters are significantly correlated. Therefore, the APT and Ktrans value of peritumor edema in gliomas may be used to differentiate glioma grades, and APT value performs better in distinguishing grade Ⅱ and Ⅲ.

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